Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart

RATIONALE: Telethonin (also known as titin-cap or t-cap) is a 19 kDa Z-disk protein with a unique β-sheet structure, hypothesized to assemble in a palindromic way with the N-terminal portion of titin and to constitute a signalosome participating in the process of cardio-mechanosensing. In addition,...

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Main Authors: Knöll, Ralph, Linke, Wolfgang A., Zou, Peijian, Mioči⋅, Snježana, Kostin, Sawa, Buyandelger, Byambajav, Ku, Ching-Hsin, Neef, Stefan, Bug, Monika, Schäfer, Katrin, Knöll, Gudrun, Felkin, Leanne E., Wessels, Johannes, Toischer, Karl, Hagn, Franz, Kessler, Horst, Didié, Michael, Quentin, Thomas, Maier, Lars S., Teucher, Nils, Unsöld, Bernhard, Schmidt, Albrecht, Birks, Emma J., Gunkel, Sylvia, Lang, Patrick, Granzier, Henk, Zimmermann, Wolfram-Hubertus, Field, Loren J., Faulkner, Georgine, Dobbelstein, Matthias, Barton, Paul JR., Sattler, Michael, Wilmanns, Matthias, Chien, Kenneth R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664427/
https://ncbi.nlm.nih.gov/pubmed/21799151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.245787
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