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Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump

The MtrCDE multidrug pump, from Neisseria gonorrhoeae, is assembled from the inner and outer membrane proteins MtrD and MtrE, which are connected by the periplasmic membrane fusion protein MtrC. Although it is clear that MtrD delivers drugs to the channel of MtrE, it remains unclear how drug deliver...

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Detalles Bibliográficos
Main Authors: Janganan, Thamarai K, Bavro, Vassiliy N, Zhang, Li, Borges-Walmsley, Maria Inês, Walmsley, Adrian R
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664412/
https://ncbi.nlm.nih.gov/pubmed/23565750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12211
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