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Deconvoluting the context-dependent role for autophagy in cancer
Autophagy (also known as macroautophagy) captures intracellular components in autophagosomes and delivers them to lysosomes, where they are degraded and recycled. Autophagy can have two functions in cancer. It can be tumour suppressive through the elimination of oncogenic protein substrates, toxic u...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3664381/ https://ncbi.nlm.nih.gov/pubmed/22534666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3262 |
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