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Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression

In many mammalian species, more than half of the initial oocyte population is eliminated by neonatal life, thus limiting the oocyte reserve for reproduction. The cause or mechanism of this major oocyte loss remains poorly understood. We examined the apoptotic pathway involved in oocyte elimination i...

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Detalhes bibliográficos
Main Authors: Ene, Adriana C., Park, Stephanie, Edelmann, Winfried, Taketo, Teruko
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664362/
https://ncbi.nlm.nih.gov/pubmed/23384561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.01.027
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