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Post-transcriptional control of gene expression by AUF1: Mechanisms, physiological targets, and regulation()

AUF1 is a family of four proteins generated by alternative pre-mRNA splicing that form high affinity complexes with AU-rich, mRNA-destabilizing sequences located within the 3′ untranslated regions of many labile mRNAs. While AUF1 binding is most frequently associated with accelerated mRNA decay, eme...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: White, Elizabeth J.F., Brewer, Gary, Wilson, Gerald M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664190/
https://ncbi.nlm.nih.gov/pubmed/23246978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2012.12.002
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