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Intravenous buprenorphine and norbuprenorphine pharmacokinetics in humans

BACKGROUND: Prescribed sublingual (SL) buprenorphine is sometimes diverted for intravenous (IV) abuse, but no human pharmacokinetic data are available following high-dose IV buprenorphine. METHODS: Plasma was collected for 72 h after administration of placebo or 2, 4, 8, 12, or 16 mg IV buprenorphin...

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Detalhes bibliográficos
Main Authors: Huestis, M.A., Cone, E.J., Pirnay, S.O., Umbricht, A., Preston, K.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663890/
https://ncbi.nlm.nih.gov/pubmed/23246635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2012.11.014
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