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Clinical neuropathology practice guide 06-2012: MGMT testing in elderly glioblastoma patients – yes, but how?

Abstract. In 2005, a seminal paper showed that glioblastoma patients aged 18 to 70, whose tumors have a methylated MGMT promoter have a better prognosis than patients with tumors carrying an unmethylated MGMT promoter. As a consequence of this and several confirmatory studies, routine MGMT testing i...

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Hlavní autoři: Berghoff, Anna S., Preusser, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: Dustri-Verlag Dr. Karl Feistle 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663470/
https://ncbi.nlm.nih.gov/pubmed/23083460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5414/NP300576
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