Manzamenones Inhibit T-Cell Protein Tyrosine Phosphatase

Manzamenones A~C (1~3) and E~F (5~6), unique oxylipin metabolites isolated from a marine sponge Plakortis sp., have been found to exhibit inhibitory activity against T-cell protein tyrosine phosphatase (TCPTP). The inhibitory activity of 2 and 5 against TCPTP was 4 times more potent than that agains...

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Detalhes bibliográficos
Main Authors: Wakuda, Yusuke, Kubota, Takaaki, Shima, Hiroshi, Okada, Tadashi, Mitsuhashi, Shinya, Aoki, Naohito, Kikuchi, Kunimi, Kobayashi, Jun’ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2006
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663405/
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