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Subcellular Clustering of the Phosphorylated WspR Response Regulator Protein Stimulates Its Diguanylate Cyclase Activity

WspR is a hybrid response regulator-diguanylate cyclase that is phosphorylated by the Wsp signal transduction complex in response to growth of Pseudomonas aeruginosa on surfaces. Active WspR produces cyclic di-GMP (c-di-GMP), which in turn stimulates biofilm formation. In previous work, we found tha...

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Autors principals: Huangyutitham, Varisa, Güvener, Zehra Tüzün, Harwood, Caroline S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663191/
https://ncbi.nlm.nih.gov/pubmed/23653447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00242-13
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