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Factors Required for Activation of Urease as a Virulence Determinant in Cryptococcus neoformans

Urease in Cryptococcus neoformans plays an important role in fungal dissemination to the brain and causing meningoencephalitis. Although urea is not required for synthesis of apourease encoded by URE1, the available nitrogen source affected the expression of URE1 as well as the level of the enzyme a...

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Detalhes bibliográficos
Main Authors: Singh, Arpita, Panting, Robert J., Varma, Ashok, Saijo, Tomomi, Waldron, Kevin J., Jong, Ambrose, Ngamskulrungroj, Popchai, Chang, Yun C., Rutherford, Julian C., Kwon-Chung, Kyung J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663189/
https://ncbi.nlm.nih.gov/pubmed/23653445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00220-13
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