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Understanding the Selectivity Mechanism of the Human Asialoglycoprotein Receptor (ASGP-R) toward Gal- and Man-type Ligands for Predicting Interactions with Exogenous Sugars

A practical approach for addressing the computer simulation of protein-carbohydrate interactions is described here. An articulated computational protocol was set up and validated by checking its ability to predict experimental data, available in the literature, and concerning the selectivity shown b...

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Detalhes bibliográficos
Main Authors: Massarelli, Ilaria, Murgia, Laura, Bianucci, Anna Maria, Chiellini, Federica, Chiellini, Emo
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662984/
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