Linkage Disequilibrium between Polymorphisms of ABCB1 and ABCC2 to Predict the Treatment Outcome of Malaysians with Complex Partial Seizures on Treatment with Carbamazepine Mono-Therapy at the Kuala Lumpur Hospital

PURPOSE: Carbamazepine (CBZ) is used as the first line of treatment of Complex Partial Seizures (CPS) in the Epilepsy Clinic, Neurology Department of Kuala Lumpur Hospital (KLH). More than 30% of the patients remain drug resistant to CBZ mono-therapy. CBZ is transported by the P-glycoprotein (P-gp)....

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Autores principales: Subenthiran, Soobitha, Abdullah, Noor Rain, Joseph, Joyce Pauline, Muniandy, Prem Kumar, Mok, Boon Teck, Kee, Chee Cheong, Ismail, Zakiah, Mohamed, Zahurin
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662793/
https://ncbi.nlm.nih.gov/pubmed/23717663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064827
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