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BcL-xL Conformational Changes upon Fragment Binding Revealed by NMR
Protein-protein interactions represent difficult but increasingly important targets for the design of therapeutic compounds able to interfere with biological processes. Recently, fragment-based strategies have been proposed as attractive approaches for the elaboration of protein-protein surface inhi...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3662666/ https://ncbi.nlm.nih.gov/pubmed/23717610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064400 |
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