RNA–Mediated Epigenetic Heredity Requires the Cytosine Methyltransferase Dnmt2

RNA–mediated transmission of phenotypes is an important way to explain non-Mendelian heredity. We have previously shown that small non-coding RNAs can induce hereditary epigenetic variations in mice and act as the transgenerational signalling molecules. Two prominent examples for these paramutations...

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Autores principales: Kiani, Jafar, Grandjean, Valérie, Liebers, Reinhard, Tuorto, Francesca, Ghanbarian, Hossein, Lyko, Frank, Cuzin, François, Rassoulzadegan, Minoo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662642/
https://ncbi.nlm.nih.gov/pubmed/23717211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003498
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