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Structural Insights on the Potential Significance of the Twin Asn-Residue Found at the Base of the Hemagglutinin 2 Stalk in All Influenza A H1N1 Strains: A Computational Study with Clinical Implications

Influenza hemagglutinin (HA) is a homotrimeric glycoprotein responsible for binding to sialic acids found in the host cell surface. HA has a prominent 75 Å-long α-helix (HA2 stalk) that contributes to overall HA structural stability. Among the H1N1 strains, a high level of predicted disorder is foun...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Cueno, Marni E., Imai, Kenichi, Ochiai, Kuniyasu
פורמט: Artigo
שפה:Inglês
יצא לאור: Mary Ann Liebert, Inc. 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662385/
https://ncbi.nlm.nih.gov/pubmed/23692362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2012.0107
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