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Toll-like receptor 7 stimulates production of specialized pro-resolving lipid mediators and promotes resolution of airway inflammation

Although specialized pro-resolving mediators (SPMs) biosynthesized from polyunsaturated fatty acids are critical for the resolution of acute inflammation, the molecules and pathways that induce their production remain elusive. Here, we show that TLR7, a receptor recognizing viral ssRNA and damaged s...

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Main Authors: Koltsida, Ourania, Karamnov, Sergey, Pyrillou, Katerina, Vickery, Thad, Chairakaki, Aikaterini-Dimitra, Tamvakopoulos, Constantin, Sideras, Paschalis, Serhan, Charles N, Andreakos, Evangelos
Formato: Artigo
Idioma:Inglês
Publicado: WILEY-VCH Verlag 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662318/
https://ncbi.nlm.nih.gov/pubmed/23584892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201891
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