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Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer

Myeloid-derived suppressor cells (MDSC) are one of the major factors limiting the efficacy of immune therapy. In a clinical trial of patients with extensive stage small cell lung cancer (SCLC), we tested the possibility that targeting MDSC can improve the induction of immune responses by a cancer va...

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Библиографические подробности
Главные авторы: Iclozan, Cristina, Antonia, Scott, Chiappori, Alberto, Chen, Dung-Tsa, Gabrilovich, Dmitry
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662237/
https://ncbi.nlm.nih.gov/pubmed/23589106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1396-8
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