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Effect of biodegradation and de novo matrix synthesis on the mechanical properties of VIC-seeded PGS-PCL scaffolds

Development of living heart valves that grow with the patient is a promising strategy for heart valve replacements in pediatric patients. Despite the active research in the field of tissue engineered heart valves, there are limited efforts to optimize the balance between biodegradation of the scaffo...

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Bibliographic Details
Main Authors: Sant, Shilpa, Iyer, Dharini, Gaharwar, Akhilesh, Patel, Alpesh, Khademhosseini, Ali
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662231/
https://ncbi.nlm.nih.gov/pubmed/23168222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2012.11.014
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