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Determination of ebselen-sensitive reactive oxygen metabolites (ebROM) in human serum based upon N,N′-diethyl-1,4-phenylenediamine oxidation

BACKGROUND: Oxidative stress occurs through free radical- and non-radical-mediated oxidative mechanisms, but these are poorly discriminated by most assays. A convenient assay for oxidants in human serum is based upon the Fe(2+)-dependent decomposition of peroxides to oxidize N,N′-diethyl-1,4-phenyle...

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Detalhes bibliográficos
Main Authors: Liang, Yongliang, Roede, James R., Dikalov, Sergey, Miller, Nana Gletsu, Dudley, Samuel C., Quyyumi, Arshed, Jones, Dean P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662006/
https://ncbi.nlm.nih.gov/pubmed/22687643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2012.06.003
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