Quasispecies and Pre-Existing Drug-Resistant Mutations of Hepatitis B Virus in Patients with Chronic Hepatitis B

BACKGROUND/AIMS: To investigate pre-existing hepatitis B virus (HBV) quasispecies and the genotypic evolution of several variants. METHODS: From six patients with lamivudine (LAM) failure, serum samples at pretreatment, 6 months of LAM therapy, and virologic breakthrough were obtained. One hundred c...

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Autori principali: Kim, Do Young, Chang, Hye Young, Lim, Sun Min, Kim, Seung Up, Park, Jun Yong, Kim, Ja Kyung, Lee, Kwan Sik, Han, Kwang-Hyub, Chon, Chae Yoon, Ahn, Sang Hoon
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661966/
https://ncbi.nlm.nih.gov/pubmed/23710315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5009/gnl.2013.7.3.329
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