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How Metformin Acts in PCOS Pregnant Women: Insights into insulin secretion and peripheral action at each trimester of gestation

OBJECTIVE: Metformin has been reported to reduce the risk of gestational diabetes (GD) in women with polycystic ovarian syndrome (PCOS). However, little is known about the mechanisms of action of this drug during pregnancy. In the attempt to fill this gap, we performed a prospective longitudinal stu...

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Detalhes bibliográficos
Main Authors: Romualdi, Daniela, De Cicco, Simona, Gagliano, Donatella, Busacca, Matteo, Campagna, Giuseppe, Lanzone, Antonio, Guido, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661808/
https://ncbi.nlm.nih.gov/pubmed/23315599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-2071
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