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A fiber-based constitutive model predicts changes in amount and organization of matrix proteins with development and disease in the mouse aorta

Decreased elastin in mice (Eln+/−) yields a functioning vascular system with elevated blood pressure and increased arterial stiffness that is morphologically distinct from wild-type mice (WT). Yet, function is retained enough that there is no appreciable effect on life span and some mechanical prope...

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Autori principali: Cheng, Jeffrey K., Stoilov, Ivan, Mecham, Robert P., Wagenseil, Jessica E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661750/
https://ncbi.nlm.nih.gov/pubmed/22790326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-012-0420-9
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