Iron-Ascorbate-Mediated Lipid Peroxidation Causes Epigenetic Changes in the Antioxidant Defense in Intestinal Epithelial Cells: Impact on Inflammation

INTRODUCTION: The gastrointestinal tract is frequently exposed to noxious stimuli that may cause oxidative stress, inflammation and injury. Intraluminal pro-oxidants from ingested nutrients especially iron salts and ascorbic acid frequently consumed together, can lead to catalytic formation of oxyge...

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Detalhes bibliográficos
Main Authors: Yara, Sabrina, Lavoie, Jean-Claude, Beaulieu, Jean-François, Delvin, Edgard, Amre, Devendra, Marcil, Valerie, Seidman, Ernest, Levy, Emile
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661745/
https://ncbi.nlm.nih.gov/pubmed/23717425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063456
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