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IL-25 improves luminal innate immunity and barrier function during parenteral nutrition

BACKGROUND: Parenteral Nutrition (PN) increases risks of infections in critically injured patients. Recently, PN was shown to reduce intestine luminal levels of the Paneth cell antimicrobial molecule, secretory phospholipase A(2) (sPLA(2)), and the goblet cell glycoprotein, MUC2. These molecules are...

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Bibliographic Details
Main Authors: Heneghan, Aaron F, Pierre, Joseph F, Gosain, Ankush, Kudsk, Kenneth A
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661688/
https://ncbi.nlm.nih.gov/pubmed/23426341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0b013e318284f510
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