Tumor Necrosis Factor-α Regulates Glucocorticoid Synthesis in the Adrenal Glands of Trypanosoma cruzi Acutely-Infected Mice. The Role of TNF-R1

Adrenal steroidogenesis is under a complex regulation involving extrinsic and intrinsic adrenal factors. TNF-α is an inflammatory cytokine produced in response to tissue injury and several other stimuli. We have previously demonstrated that TNF-R1 knockout (TNF-R1(−/−)) mice have a dysregulated synt...

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Autori principali: Villar, Silvina R., Ronco, M. Teresa, Fernández Bussy, Rodrigo, Roggero, Eduardo, Lepletier, Ailin, Manarin, Romina, Savino, Wilson, Pérez, Ana Rosa, Bottasso, Oscar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661674/
https://ncbi.nlm.nih.gov/pubmed/23717489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063814
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