Decreased RB1 mRNA, Protein, and Activity Reflect Obesity-Induced Altered Adipogenic Capacity in Human Adipose Tissue

Retinoblastoma (Rb1) has been described as an essential player in white adipocyte differentiation in mice. No studies have been reported thus far in human adipose tissue or human adipocytes. We aimed to investigate the possible role and regulation of RB1 in adipose tissue in obesity using human samp...

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Detalhes bibliográficos
Main Authors: Moreno-Navarrete, José María, Petrov, Petar, Serrano, Marta, Ortega, Francisco, García-Ruiz, Estefanía, Oliver, Paula, Ribot, Joan, Ricart, Wifredo, Palou, Andreu, Bonet, Mª Luisa, Fernández-Real, José Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661645/
https://ncbi.nlm.nih.gov/pubmed/23315497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0977
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