Role of Nitric Oxide and CCAAT/Enhancer-Binding Protein Transcription Factor in Statin-Dependent Induction of Heme Oxygenase-1 in Mouse Macrophages

The effect of statins on heme oxygenase-1 (HO-1) was compared in 2 murine cell lines, RAW 264.7 and J774A.1 cell lines, and in primary peritoneal macrophages of BALB/c or C57BL/6 mice. The role of endogenous nitric oxide and the type of transcription factors involved were explored. Simvastatin and f...

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Bibliografiske detaljer
Main Authors: Mouawad, Charbel A., Mrad, May F., Al-Hariri, Moustafa, Soussi, Hiba, Hamade, Eva, Alam, Jawed, Habib, Aïda
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661457/
https://ncbi.nlm.nih.gov/pubmed/23717538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064092
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