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Exceptionally Long CDR3H Are Not Isotype Restricted in Bovine Immunoglobulins

Exceptionally long third complementarity determining regions of the heavy chain (CDR3H) were previously described as a specificity of bovine IgG and IgM immunoglobulins. In addition, the genomic organization of the immunoglobulin heavy chain locus remains to be elucidated with a special focus on the...

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Autors principals: Walther, Stefanie, Czerny, Claus-Peter, Diesterbeck, Ulrike S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661452/
https://ncbi.nlm.nih.gov/pubmed/23717573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064234
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