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An unexpected role of neuroligin-2 in regulating KCC2 and GABA functional switch
BACKGROUND: GABA(A) receptors are ligand-gated Cl(-) channels, and the intracellular Cl(-) concentration governs whether GABA function is excitatory or inhibitory. During early brain development, GABA undergoes functional switch from excitation to inhibition: GABA depolarizes immature neurons but hy...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661362/ https://ncbi.nlm.nih.gov/pubmed/23663753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-23 |
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