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A new strategy to target regulatory T cells in solid tumors

The depletion of regulatory T cells (Tregs) is a promising therapeutic strategy to enhance antitumor immune responses. Our recent findings indicate that low doses of arsenic trioxide can delay tumor growth in murine models of colon and breast cancer by depleting Tregs through oxidative and nitrosati...

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Détails bibliographiques
Auteurs principaux: Thomas-Schoemann, Audrey, Batteux, Frédéric, Alexandre, Jérôme
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661163/
https://ncbi.nlm.nih.gov/pubmed/23802078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23338
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