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ACTL6a Enforces the Epidermal Progenitor State by Suppressing SWI/SNF-Dependent Induction of KLF4

Somatic progenitors suppress differentiation to maintain tissue self-renewal. The mammalian SWI/SNF chromatin-remodeling complex regulates nucleosome packaging to control differentiation in embryonic and adult stem cells. Catalytic Brg1 and Brm subunits are required for these impacts, however, roles...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bao, Xiaomin, Tang, Jiong, Lopez-Pajares, Vanessa, Tao, Shiying, Qu, Kun, Crabtree, Gerald R., Khavari, Paul A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661004/
https://ncbi.nlm.nih.gov/pubmed/23395444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.12.014
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