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Succinate dehydrogenase (SDHx) mutations in pituitary tumors: could this be a new role for mitochondrial complex II and/or Krebs cycle defects?

Succinate dehydrogenase (SDH) or mitochondrial complex II is a multimeric enzyme that is bound to the inner membrane of mitochondria and has a dual role as it serves both as a critical step of the tricarboxylic acid or Krebs cycle and as a member of the respiratory chain that transfers electrons dir...

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Detalhes bibliográficos
Main Authors: Xekouki, Paraskevi, Stratakis, Constantine A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660975/
https://ncbi.nlm.nih.gov/pubmed/22889736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-12-0118
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