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The preparation of HL-60 cells vaccine expressing BCG heat shock protein 70 and detection of its immunogenicity in vitro

Gene-modified cell vaccines are the best way to achieve the immunotherapy for all types of acute leukemia. In this study, the recombinant eukaryotic expression vector (pDisplay-HSP70) of heat shock protein 70 (HSP70) of Bacille Calmette-Guérin (BCG) was constructed by amplifying the whole BCG HSP70...

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Main Authors: Li, Xiao-Ling, Zhao, Yan-Xia, Sun, Li-Rong, Yang, Jing, Xu, Hui-Juan
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660756/
https://ncbi.nlm.nih.gov/pubmed/22894947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.21321
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