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Increased Cholesterol Content in Gammadelta (γδ) T Lymphocytes Differentially Regulates Their Activation

Gammadelta (γδ) T lymphocytes respond quickly upon antigen encounter to produce a cytokine response. In this study, we sought to understand how functions of γδ T cells are differentially regulated compared to αβ T cells. We found that cholesterol, an integral component of the plasma membrane and a r...

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Detalhes bibliográficos
Main Authors: Cheng, Hsin-Yuan, Wu, Runpei, Gebre, Abraham K., Hanna, Richard N., Smith, Dan J., Parks, John S., Ley, Klaus, Hedrick, Catherine C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660587/
https://ncbi.nlm.nih.gov/pubmed/23704936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063746
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