Transcription Factors MYOCD, SRF, Mesp1 and SMARCD3 Enhance the Cardio-Inducing Effect of GATA4, TBX5, and MEF2C during Direct Cellular Reprogramming

Transient overexpression of defined combinations of master regulator genes can effectively induce cellular reprogramming: the acquisition of an alternative predicted phenotype from a differentiated cell lineage. This can be of particular importance in cardiac regenerative medicine wherein the heart...

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Autores principales: Christoforou, Nicolas, Chellappan, Malathi, Adler, Andrew F., Kirkton, Robert D., Wu, Tianyi, Addis, Russell C., Bursac, Nenad, Leong, Kam W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660533/
https://ncbi.nlm.nih.gov/pubmed/23704920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063577
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