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Enriched Environment Prevents Hypobaric Hypoxia Induced Memory Impairment and Neurodegeneration: Role of BDNF/PI3K/GSK3β Pathway Coupled with CREB Activation

Adverse environmental conditions such as hypobaric hypoxia (HH) cause memory impairment by affecting cellular machinery leading to neurodegeneration. Providing enriched environment (EE) is found to be beneficial for curing several neurodegenerative disorders. The protective role of EE in preventing...

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Bibliografiske detaljer
Main Authors: Jain, Vishal, Baitharu, Iswar, Prasad, Dipti, Ilavazhagan, Govindasamy
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660501/
https://ncbi.nlm.nih.gov/pubmed/23704876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062235
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