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Local administration of TLR ligands rescues the function of tumor-infiltrating CD8-T cells and enhances the antitumor effect of lentivector immunization
Cancer vaccines, so far, have shown limited effect to control the growth of established tumors due largely to effector failure of the antitumor immune responses. Tumor lesion is characterized as chronic indolent inflammation in which the effector function of tumor infiltrating lymphocytes (TILs) is...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3660440/ https://ncbi.nlm.nih.gov/pubmed/23610140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203470 |
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