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Role for Subgenomic mRNA in Host Translation Inhibition during Sindbis Virus Infection of Mammalian Cells
Sindbis virus subgenomic mRNA is efficiently translated in infected vertebrate cells whereas host translation is shut-off. Deletions in the 5′ UTR of the subgenomic mRNA were made to investigate its role in viral gene expression. Deletion of nucleotides 1-10 and 11-20 caused a small plaque phenotype...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3660432/ https://ncbi.nlm.nih.gov/pubmed/23601784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.03.022 |
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