Quorum Sensing Negatively Regulates Multinucleate Cell Formation during Intracellular Growth of Burkholderia pseudomallei in Macrophage-Like Cells

Burkholderia pseudomallei is a Gram-negative environmental bacterium and the causative agent of melioidosis, a potentially fatal, acute or chronic disease endemic in the tropics. Acyl homoserine lactone (AHL)-mediated quorum sensing and signalling have been associated with virulence and biofilm form...

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Autors principals: Horton, Rachel E., Grant, Gary D., Matthews, Ben, Batzloff, Michael, Owen, Suzzanne J., Kyan, Stephanie, Flegg, Cameron P., Clark, Amanda M., Ulett, Glen C., Morrison, Nigel, Peak, Ian R., Beacham, Ifor R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660431/
https://ncbi.nlm.nih.gov/pubmed/23704903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063394
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