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Human Fc receptor-like 5 binds intact IgG via mechanisms distinct from that of Fc-receptors ()
Fc receptor-like 5 (FCRL5) regulates BCR signaling and has been reported to bind aggregated IgG. Using surface plasmon resonance, we analyzed the interaction of native IgG samples with FCRL5, revealing a complex binding mechanism, where isotype is just one factor. FCRL5 bound IgG1 and IgG4 with appr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3660407/ https://ncbi.nlm.nih.gov/pubmed/23616577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202860 |
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