Golden Berry-Derived 4β-hydroxywithanolide E for Selectively Killing Oral Cancer Cells by Generating ROS, DNA Damage, and Apoptotic Pathways

BACKGROUND: Most chemotherapeutic drugs for killing cancer cells are highly cytotoxic in normal cells, which limits their clinical applications. Therefore, a continuing challenge is identifying a drug that is hypersensitive to cancer cells but has minimal deleterious effects on healthy cells. The ai...

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Detalhes bibliográficos
Main Authors: Chiu, Chien-Chih, Haung, Jo-Wen, Chang, Fang-Rong, Huang, Kuang-Jing, Huang, Hsuan-Min, Huang, Hurng-Wern, Chou, Chon-Kit, Wu, Yang-Chang, Chang, Hsueh-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660349/
https://ncbi.nlm.nih.gov/pubmed/23705007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064739
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