Production of Multiple Transgenic Yucatan Miniature Pigs Expressing Human Complement Regulatory Factors, Human CD55, CD59, and H-Transferase Genes

The present study was conducted to generate transgenic pigs coexpressing human CD55, CD59, and H-transferase (HT) using an IRES-mediated polycistronic vector. The study focused on hyperacute rejection (HAR) when considering clinical xenotransplantation as an alternative source for human organ transp...

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Detalhes bibliográficos
Main Authors: Jeong, Young-Hee, Park, Chi-Hun, Jang, Gun-Hyuk, Jeong, Yeun-Ik, Hwang, In-Sung, Jeong, Yeon-woo, Kim, Yu-Kyung, Shin, Taeyoung, Kim, Nam-Hyung, Hyun, Sang-Hwan, Jeung, Eui-Bae, Hwang, Woo-Suk
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660325/
https://ncbi.nlm.nih.gov/pubmed/23704897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063241
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