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Functional Interrogation of an Odorant Receptor Locus Reveals Multiple Axes of Transcriptional Regulation

The odorant receptor (OR) genes constitute the largest mammalian gene family and are expressed in a monogenic and monoallelic fashion, through an unknown mechanism that likely exploits positive and negative regulation. We devised a genetic strategy in mice to examine OR selection by determining the...

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Detalhes bibliográficos
Main Authors: Fleischmann, Alexander, Abdus-Saboor, Ishmail, Sayed, Atef, Shykind, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660300/
https://ncbi.nlm.nih.gov/pubmed/23700388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001568
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