MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation

MicroRNA-34b down-regulation in acute myeloid leukemia was previously shown to induce CREB overexpression, thereby causing leukemia proliferation in vitro and in vivo. The role of microRNA-34b and CREB in patients with myeloid malignancies has never been evaluated. We examined microRNA-34b expressio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Pigazzi, Martina, Manara, Elena, Bresolin, Silvia, Tregnago, Claudia, Beghin, Alessandra, Baron, Emma, Giarin, Emanuela, Cho, Er-Chieh, Masetti, Riccardo, Rao, Dinesh S., Sakamoto, Kathleen M., Basso, Giuseppe
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Ferrata Storti Foundation 2013
विषय:
Original Articles and Brief Reports
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659992/
https://ncbi.nlm.nih.gov/pubmed/23100280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.070664
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