Reprogramming of Fibroblasts From Older Women With Pelvic Floor Disorders Alters Cellular Behavior Associated With Donor Age

We aimed to derive induced pluripotent stem cell (iPSC) lines from vaginal fibroblasts from older women with pelvic organ prolapse. We examined the effect of donor age on iPSCs and on the cells redifferentiated from these iPSCs. Vaginal fibroblasts were isolated from younger and older subjects for r...

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Detalhes bibliográficos
Main Authors: Wen, Yan, Wani, Prachi, Zhou, Lu, Baer, Tom, Phadnis, Smruti Madan, Reijo Pera, Renee A., Chen, Bertha
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2013
Assuntos:
Tissue-Specific Progenitor and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659753/
https://ncbi.nlm.nih.gov/pubmed/23341439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2012-0092
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