Comparative Analysis of Targeted Differentiation of Human Induced Pluripotent Stem Cells (hiPSCs) and Human Embryonic Stem Cells Reveals Variability Associated With Incomplete Transgene Silencing in Retrovirally Derived hiPSC Lines

Functional hepatocytes, cardiomyocytes, neurons, and retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (hESCs) or human induced pluripotent stem cells (hiPSCs) could provide a defined and renewable source of human cells relevant for cell replacement therapies, drug disco...

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Main Authors: Toivonen, Sanna, Ojala, Marisa, Hyysalo, Anu, Ilmarinen, Tanja, Rajala, Kristiina, Pekkanen-Mattila, Mari, Äänismaa, Riikka, Lundin, Karolina, Palgi, Jaan, Weltner, Jere, Trokovic, Ras, Silvennoinen, Olli, Skottman, Heli, Narkilahti, Susanna, Aalto-Setälä, Katriina, Otonkoski, Timo
Formato: Artigo
Idioma:Inglês
Publicado: AlphaMed Press 2013
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem (iPS) Cells
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659749/
https://ncbi.nlm.nih.gov/pubmed/23341440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2012-0047
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