Oleanolic Acid Diminishes Liquid Fructose-Induced Fatty Liver in Rats: Role of Modulation of Hepatic Sterol Regulatory Element-Binding Protein-1c-Mediated Expression of Genes Responsible for De Novo Fatty Acid Synthesis

Oleanolic acid (OA), contained in more than 1620 plants and as an aglycone precursor for naturally occurred and synthesized triterpenoid saponins, is used in China for liver disorders in humans. However, the underlying liver-protecting mechanisms remain largely unknown. Here, we found that treatment...

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Hlavní autoři: Liu, Changjin, Li, Ying, Zuo, Guowei, Xu, Wenchun, Gao, Huanqing, Yang, Yifan, Yamahara, Johji, Wang, Jianwei, Li, Yuhao
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659486/
https://ncbi.nlm.nih.gov/pubmed/23737835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/534084
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