Oocyte-derived R-spondin2 promotes ovarian follicle development

R-spondin proteins are adult stem cell growth factors capable of stimulating gut development by activating LGR4, 5, and 6 receptors to promote Wnt signaling. Although multiple Wnt ligands and cognate Frizzled receptors are expressed in the ovary, their physiological roles are unclear. Based on bioin...

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Bibliographic Details
Main Authors: Cheng, Yuan, Kawamura, Kazuhiro, Takae, Seido, Deguchi, Masashi, Yang, Qing, Kuo, Calvin, Hsueh, Aaron J. W.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2013
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659360/
https://ncbi.nlm.nih.gov/pubmed/23407710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-223412
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