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Mitochondria-targeted antioxidant promotes recovery of skeletal muscle mitochondrial function after burn trauma assessed by in vivo (31)P nuclear magnetic resonance and electron paramagnetic resonance spectroscopy

Burn injury causes a major systemic catabolic response that is associated with mitochondrial dysfunction in skeletal muscle. We investigated the effects of the mitochondria-targeted peptide antioxidant Szeto-Schiller 31 (SS-31) on skeletal muscle in a mouse burn model using in vivo phosphorus-31 nuc...

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Main Authors: Righi, Valeria, Constantinou, Caterina, Mintzopoulos, Dionyssios, Khan, Nadeem, Mupparaju, S. P., Rahme, Laurence G., Swartz, Harold M., Szeto, Hazel H., Tompkins, Ronald G., Tzika, A. Aria
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659352/
https://ncbi.nlm.nih.gov/pubmed/23482635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-220764
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