Tumor Cell Clone Expressing the Membrane-bound Form of IL-12p35 Subunit Stimulates Antitumor Immune Responses Dominated by CD8(+) T Cells

IL-12 is a secretory heterodimeric cytokine composed of p35 and p40 subunits. IL-12 p35 and p40 subunits are sometimes produced as monomers or homodimers. IL-12 is also produced as a membrane-bound form in some cases. In this study, we hypothesized that the membrane-bound form of IL-12 subunits may...

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Bibliographische Detailangaben
Hauptverfasser: Lim, Hoyong, Do, Seon Ah, Park, Sang Min, Kim, Young Sang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Association of Immunologists 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659257/
https://ncbi.nlm.nih.gov/pubmed/23700396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2013.13.2.63
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